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Munakata and Namekawa will Assess mice with standard and mutated versions of your chromatin remodeler. Given that the mice grow and experienced, they can observe whether the presence or absence of this protein triggers discrepancies while in the arrangement of DNA spools in the animals’ oocytes. And they'll keep track of regardless of whether this, consequently, alters the pattern of gene expression eventually.

“We don’t know how these cells are maintained for decades,” states Namekawa. “We want to know The key of the system.

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This protein might “create and sustain the chromatin condition,” suggests Namekawa — trying to keep the spools in place plus the oocytes genetically primed because the mouse matures.

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